This is the same speed as walking or using a raft. Hence to run is to simply hope that one can dodge the meleeing, and put barriers between oneself and the Magical, swimming, and /or flying creatures.
Of course, a wizard could cast a Field spell, such as Paralyze field, which could assist in this process, if it does not fizzle and lasts long enough. But this will have minimal effect on any Magical creatures and /or high Resisting Magic, creatures. Besides it uses a Dragon Tooth and will be required-again if the runner(s) likely-do encounter other creatures ahead, with less mana, to do such with.
A Charm of Swiftness can help a person with Path Movement on using a mouse, to go about 5% faster.
In a group, it is sometimes appropriate to yell the formal: "Run Away!" less-formal "Out," or "Water," then "no mana," or even "run."